ELL707
| ELL707 | |
|---|---|
| Systems Biology | |
| Credits | 3 |
| Structure | 3-0-0 |
| Pre-requisites | ELL225 |
| Overlaps | |
ELL707 : Systems Biology
[edit]MODELS: Variables and parameters, Law of mass action, Representations : Deterministic vs stochastic, Spatial aspects, Examples of core processes: Gene expression, Protein degradation, Phosphorylation. DYNAMICS: Equilibrium solutions, Bifurcations, Switches, Bistability, Pulses and Oscillations, Circadian Rhythms and Clocks, Spatial patterns. Morphogenesis and Development. CONTROL MECHANISMS: Performance Goals, Integral Feedback Control, Homeostasis and Perfect Adaptation, Bacterial Chemotaxis, Feedforward Loops, Fold Change Detection, Robustness to Perturbations, Tradeoffs, Internal Model Principle.