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CLL778

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CLL778
Interfacial Behaviour and Transport of Biomolecules
Credits 3
Structure 3-0-0
Pre-requisites CLL110
Overlaps CYL669, SBL705, SBV885

CLL778 : Interfacial Behaviour and Transport of Biomolecules

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Structure of biomacromolecules. Attributes of biomacromolecules: size, charge, hydrophobicity. Characteristics of surface and interfaces: roughness, charge, hydrophobicity. Interactions between biomacromolecules and interfaces: adsorption, specific binding. Aggregation of proteins, modeling of the underlying phenomena. Elasticity of adsorbed macro-molecules at interfaces. Equilibrium and transient description of transport of biomolecules through intra- and extracellular space. Governing equations applied to biological systems: conservation laws, flux equations, Fickian and non-Fickian diffusion, diffusion with reaction/ binding, electrochemical transport. Constitutive laws and solution methods applied to biological systems. Adsorption isotherms and transport across membrane.