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BBL734

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BBL734
Metabolic Regulation and Engineering
Credits 3
Structure 3-0-0
Pre-requisites BBL331, BBL431
Overlaps

BBL734 : Metabolic Regulation and Engineering

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Regulatory mechanisms for control of enzyme synthesis - an overview; Control of enzyme activity- proteolysis, covalent modification and ligand binding; Metabolic control theory and metabolic flux analysis; Metabolic regulation of a few major metabolic pathways especially those relevant to bioprocess industries; Pathway engineering; Application of gene cloning in re-directing cellular metabolism for over-production of a few industrial products; Strategies to overcome regulatory mechanisms for over-production of several industrially important primary and secondary metabolites such as alcohols, organic acids, amino acids, enzymes and therapeutic compounds.