ApL740
| ApL740 | |
|---|---|
| Mechanics of Biological Cells | |
| Credits | 4 |
| Structure | 3-0-2 |
| Pre-requisites | EC 75 |
| Overlaps | |
ApL740 : Mechanics of Biological Cells
[edit]Theoretical Part: Basic Introduction to mechano-biology, Concept of Length Scale, Mechanical Forces, Mass, Stiffness and Damping of Proteins, Thermal Forces and Diffusion, Chemical Forces, Polymer Mechanics. Intracellular Mechanics: Structures of Cytoskeleton Filaments, Dynamics of Cell Filaments, Molecular motors, Introduction to Entropic Elasticity and Persistence Length, Force Generation by Cytoskeleton Filaments. Extracellular Mechanics: The Extracellular matrix (ECM), Cell-ECM Interactions, Cell Migration, Forces and Adhesion. Tissue Mechanics: Cell-cell Assemblies, Tissue Material Behavior, Introduction to Linear Viscoelasticity, Concept of Constitutive Modeling. Experimental Part: Different Experimental Methods for Probing Cell Mechanical Properties. Intro to indentation, Aspiration, Twezeer, Nano patterened platform based techniques etc. ApL 742 Advanced Biomechanics 4 Credits (3-0-2) Basic Introduction to biomechanics of tissue/cells,Concept of Length Scale, Mechanical Forces, Mass, Stiffness and Damping of Proteins, Thermal Forces and Diffusion, Chemical Forces, Polymer Mechanics. Tissue Mechanics: Cell-cell Assemblies,Tissue Material Behavior, Introduction to Linear Viscoelasticity, Concept of Constitutive Modeling, Nonlinear continuum frame work of biomechancial simulation, special topic on tissue-device interaction, orthopedic/spinal implants etc. Intracellular Mechanics: Structures of Cytoskeleton Filaments, Dynamics of Cell Filaments, Molecular motors, Introduction to Entropic Elasticity and Persistence Length, Force Generation by Cytoskeleton Filaments. Extracellular Mechanics: The Extracellular matrix (ECM), cell-ECM Interactions, Cell Migration, Forces and Adhesion. Experimental Part Different Experimental Methods for Probing Cell & Tissue Mechanical Properties. Intro to Indentation, Aspiration, twezeer, Nanopatterened platform based techniques etc.