CLL780
| CLL780 | |
|---|---|
| Bioprocessing and Bioseparations | |
| Credits | 3 |
| Structure | 3-0-0 |
| Pre-requisites | CLL271 |
| Overlaps | BEL703, BEL820 |
CLL780 : Bioprocessing and Bioseparations
Introduction to the different unit operations utilized in production of biotech drugs in the areas of upstream processing, harvest, and downstream processing. Introduction to analytical methods used for characterization of biotech products and processes (high performance liquid chromatography, mass spectrophotometry, capillary electrophoresis, near infrared spectroscopy,UV spectroscopy). Optimization of biotech processes - unit operation specific optimization vs. process optimization, process intensification, statistical data analysis. Scale-up of different unit operations utilized in bioprocessing: procedures, issues that frequently occur and possible solutions. Good Manufacturing Practices (GMP): need, principles and key practical issues. Process validation: basics, planning and Courses of Study 2024-2025 Chemical Engineering 133implementation. Industrial case studies in bioprocessing. Current topics in bioprocessing and bioseparations: Quality by Design and Process Analytical Technology.