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SBL708

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SBL708
Epigenetics in Human Health and Disease
Credits 3
Structure 3-0-0
Pre-requisites EC 75 and BEL110 or CYL110 or CYL120 or
Overlaps

SBL708 : Epigenetics in Human Health and Disease

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Equivalent Introduction – overview of epigenetics in human health and disease; Epigenetic mechanisms – basic mechanisms: DNA methylation and genome imprinting –role of DNA methylation; Epigenetics in cancer Biology – global and region specific changes and effects on transcription; DNA methylation and repeat instability diseases; Epigenetic reprogramming and role of DNA methylation in mammalian development –role in embryogenesis; Epigenetics in pluriprotency and differentiation of embryonic stems cells; MicroRNA in carcinogenesis – mechanisms and potential therapeutic options; Epigenetic regulation Courses of Study 2024-2025 Biological Sciences 352of viruses by the host –role in pathogenesis; methods in epigenetics- methylation patterns and histone modifications; Case studies from literature, evolving and emerging areas of interest.